Our formulations are guided by scientific research to ensure effective, nature-powered support for your dog's wellness.
Joint HealthEfficacy for Degenerative Joint Disease
The Findings: Clinical trials showed that GLM extract is well-tolerated and effective in managing symptoms for dogs diagnosed with presumptive degenerative joint disease.
Pollard, B., et al. (2006). "Clinical efficacy and tolerance of an extract of green-lipped mussel in dogs." New Zealand Veterinary Journal, 54(3), 114-118. https://doi.org/10.1080/00480169.2006.36622
Mobility StudyImprovement in Arthritic Signs
The Findings: This study demonstrated significant improvements in joint mobility and a reduction in arthritic signs in dogs supplemented with Green-Lipped Mussel over a six-week period.
Bierer, T. L., & Bui, L. M. (2002). "Improvement of arthritic signs in dogs fed green-lipped mussel (Perna canaliculus)." The Journal of Nutrition, 132(6), 1634S-1636S.
Pain ManagementEffects on Behavior and Function
The Findings: Research indicated that a diet enriched with GLM positively influenced pain behavior and physical functioning in dogs suffering from clinical osteoarthritis.
Rialland, P., et al. (2013). "Effect of a diet enriched with green-lipped mussel on pain behavior and functioning in dogs." Canadian Journal of Veterinary Research, 77(1), 66-74. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3524818/
Veterinary ReviewComprehensive Veterinary Trial Review
The Findings: A detailed review of various veterinary trials confirming that GLM is a scientifically supported complementary therapy for canine osteoarthritis.
Eason, C. T., et al. (2018). "Greenshell™ mussels: a review of veterinary trials and future research directions." Veterinary Sciences, 5(2), 36. https://doi.org/10.3390/vetsci5020036
Arthritis SignsReduced Pain & Swelling
The Findings: In a double-blind study of 31 dogs with varying degrees of arthritis, dogs fed green-lipped mussel powder showed significant improvement in total arthritis scores — with vets individually scoring joint pain, swelling, crepitus and range of movement.
Bui, L. M., & Bierer, T. L. (2003). Veterinary Therapeutics, 4, 397–407. https://pubmed.ncbi.nlm.nih.gov/15136981/
OsteoarthritisMeasured Against an NSAID
The Findings: In a randomised, double-blinded trial, 45 dogs with radiographically confirmed osteoarthritis were given green-lipped mussel, an NSAID (carprofen), or placebo over 8 weeks. Researchers concluded GLM may be beneficial for dogs — including where NSAIDs cannot be used.
Hielm-Björkman, A., Tulamo, R-M., Salonen, H., & Raekallio, M. (2009). Evidence-Based Complementary and Alternative Medicine, 6, 365–373. https://pmc.ncbi.nlm.nih.gov/articles/PMC3525174/
Gait AnalysisObjective Activity (Measured by Sensor)
The Findings: In a double-blinded, placebo-controlled cross-over trial, 32 New Zealand working farm dogs with musculoskeletal abnormalities each received two doses of green-lipped mussel extract and a placebo, 8 weeks apiece with a 4-week washout in between, while wearing a collar-mounted accelerometer that recorded movement continuously. Treatment with the mussel extract increased peak activity in dogs with signs of joint disease. The researchers concluded that even mildly affected working dogs may benefit.
Cave, N., Bolton, S., & Cogger, N. (2024). "A pilot study to detect the effects of a green-lipped mussel (Perna canaliculus) nutraceutical on working farm dogs with musculoskeletal abnormalities using accelerometry." New Zealand Veterinary Journal, 72(6), 323–333. https://pubmed.ncbi.nlm.nih.gov/39112015/
Greenshell™ Mussel Powder for Senior Dogs for Mobility & Joint Comfort
$21.00